Any feedback?
Literature summary for 4.1.1.19 extracted from
- Biosynthetic and biodegradative ornithine and arginine decarboxylases from Escherichia coli (1983), Methods Enzymol., 94, 125-134.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Escherichia coli |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 74000 | - |
4 * 74000, biosynthetic arginine decarboxylase | Escherichia coli |
| 82000 | - |
2 * or 10 * 82000, degradative arginine decarboxylase | Escherichia coli |
| 82000 | - |
10 * or 1 * 82000, degradative arginine decarboxylase | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Arg | Escherichia coli | 2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| biosynthetic arginine decarboxylase and synthetic arginine decarboxylase | Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 16.4 | - |
biosynthetic arginine decarboxylase | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Arg | 2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH | Escherichia coli | ? | - |
? | |
| L-arginine | - |
Escherichia coli | agmatine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| decamer | 10 * or 1 * 82000, degradative arginine decarboxylase | Escherichia coli |
| dimer | 2 * or 10 * 82000, degradative arginine decarboxylase | Escherichia coli |
| tetramer | 4 * 74000, biosynthetic arginine decarboxylase | Escherichia coli |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
degradative arginine decarboxylase | Escherichia coli |
| 8.4 | - |
biosynthetic arginine decarboxylase | Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | stimulates | Escherichia coli | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
