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Literature summary for 4.1.1.18 extracted from
- Structure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activity (2010), Proc. Natl. Acad. Sci. USA, 107, 22499-22504.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| cage-like complex of about 3.3 MDa consisting of two LdcI (81 kDa) decamers and up to five RavA (56 kDa) hexamers, hanging drop vapor diffusion method, using | Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ppGpp | LdcI activity is strongly inhibited by the binding of ppGpp. The RavA-LdcI interaction reduces the inhibition of LdcI activity by ppGpp in vitro as well as in vivo | Escherichia coli |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 81000 | - |
10 * 81000, X-ray crystallography | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodecamer | 10 * 81000, X-ray crystallography | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| inducible lysine decarboxylase | - |
Escherichia coli |
| LdcI/CadA | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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