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Literature summary for 4.1.1.12 extracted from

  • Richardson, G.; Ding, H.; Rocheleau, T.; Mayhew, G.; Reddy, E.; Han, Q.; Christensen, B.M.; Li, J.
    An examination of aspartate decarboxylase and glutamate decarboxylase activity in mosquitoes (2009), Mol. Biol. Rep., 37, 3199-3205.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.12

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Aedes aegypti

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8
-
 L-aspartate in 0.2 M phosphate buffer (pH 7.0) containing 0.1 mM pyridoxal 5'-phosphate, at 25°C Aedes aegypti

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000
-
 gel filtration Aedes aegypti

Organism

Organism UniProt Comment Textmining
Aedes aegypti
-
-
-

Purification (Commentary)

Purification (Comment) Organism
chitin bead column chromatography, Mono-Q column chromatography, hydroxylapatite column chromatography, and gel filtration Aedes aegypti

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
 Aedes aegypti
-
pupa
-
 Aedes aegypti
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate more than 95% of the substrate is converted to beta-alanine during a 20 min incubation period Aedes aegypti beta-alanine + CO2
-
 ?
additional information no activity with L-glutamate Aedes aegypti ?
-
 ?

Subunits

Subunits Comment Organism
dimer
-
 Aedes aegypti

Synonyms

Synonyms Comment Organism
ADC
-
 Aedes aegypti

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Aedes aegypti