Protein Variants | Comment | Organism |
---|---|---|
D11E | totally inactive in catalysis | Burkholderia cepacia |
D11N | totally inactive in catalysis | Burkholderia cepacia |
D11S | totally inactive in catalysis | Burkholderia cepacia |
D181N | totally inactive in catalysis | Burkholderia cepacia |
additional information | point mutations on 29 conserved charged and/or polar residues are generated and characterized | Burkholderia cepacia |
N178D | defective in catalysis | Burkholderia cepacia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-2-haloalkanoic acid + H2O | Burkholderia cepacia | - |
D-2-hydroxyalkanoic acid + halide | - |
? | |
L-2-haloalkanoic acid + H2O | Burkholderia cepacia MBA4 | - |
D-2-hydroxyalkanoic acid + halide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Burkholderia cepacia | - |
MBA4 | - |
Burkholderia cepacia MBA4 | - |
MBA4 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-2-haloacid + H2O | - |
Burkholderia cepacia | (R)-2-hydroxyacid + halide | - |
? | |
(S)-2-haloacid + H2O | - |
Burkholderia cepacia MBA4 | (R)-2-hydroxyacid + halide | - |
? | |
L-2-haloalkanoic acid + H2O | - |
Burkholderia cepacia | D-2-hydroxyalkanoic acid + halide | - |
? | |
L-2-haloalkanoic acid + H2O | - |
Burkholderia cepacia MBA4 | D-2-hydroxyalkanoic acid + halide | - |
? | |
monochloroacetate + H2O | - |
Burkholderia cepacia | glycolate + HCl | - |
? | |
monochloroacetate + H2O | - |
Burkholderia cepacia MBA4 | glycolate + HCl | - |
? |