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Literature summary for 3.6.5.4 extracted from

  • Farmery, M.; Macao, B.; Larsson, T.; Samuelsson, T.
    Binding of GTP and GDP induces a significant conformational change in the GTPase domain of Ffh, a bacterial homologue of the SRP 54 kDa subunit (1998), Biochim. Biophys. Acta, 1385, 61-68.
    View publication on PubMed

Application

Application Comment Organism
medicine protein translocation across the endoplasmic reticulum Mycoplasma mycoides

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mycoplasma mycoides

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
GTP
-
Mycoplasma mycoides

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33760
-
MALDI-MS Mycoplasma mycoides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP + H2O Mycoplasma mycoides
-
GMP + phosphate
-
?
GDP + H2O Mycoplasma mycoides Ffh
-
GMP + phosphate
-
?
GTP + H2O Mycoplasma mycoides
-
GDP + phosphate
-
?
GTP + H2O Mycoplasma mycoides Ffh
-
GDP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Mycoplasma mycoides
-
Ffh
-
Mycoplasma mycoides Ffh
-
Ffh
-

Purification (Commentary)

Purification (Comment) Organism
-
Mycoplasma mycoides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP + H2O
-
Mycoplasma mycoides GMP + phosphate
-
?
GDP + H2O
-
Mycoplasma mycoides Ffh GMP + phosphate
-
?
GTP + H2O
-
Mycoplasma mycoides GDP + phosphate
-
?
GTP + H2O
-
Mycoplasma mycoides Ffh GDP + phosphate
-
?