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Literature summary for 3.6.5.3 extracted from

  • Stolboushkina, E.; Nikonov, S.; Nikulin, A.; Blaesi, U.; Manstein, D.J.; Fedorov, R.; Garber, M.; Nikonov, O.
    Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits (2008), J. Mol. Biol., 382, 680-691.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
full-sized alphabetagamma heterotrimeric aIF2 in the nucleotide-free form, and aIF2alphagamma dimer, X-ray diffraction structure determination and analysis at 2.8 A resolution Saccharolobus solfataricus

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc-binding domain in the beta-subunit Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q980A5
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information aIF2 shows very high conformational flexibility in the alpha- and beta-subunits probably required for interaction of aIF2 with the small ribosomal subunit, overview Saccharolobus solfataricus ?
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Subunits

Subunits Comment Organism
More aIF2 shows very high conformational flexibility in the alpha- and beta-subunits probably required for interaction of aIF2 with the small ribosomal subunit, structure comparison of the heterotrimer aIF2alphabetagamma to aIF2alphagamma and aIF2betagamma heterodimers, structure of subunits, overview Saccharolobus solfataricus
trimer heterotrimer, the archaeal factor aIF2 is formed upon the 1:1:1 association of three subunits: alpha, beta, and gamma Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
aIF2
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Saccharolobus solfataricus
archaeal translation initiation factor 2
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Saccharolobus solfataricus
translation initiation factor 2
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Saccharolobus solfataricus