Literature summary for 3.6.5.3 extracted from

Dubovaya, V.I.; Kolosov, P.M.; Alkalaeva, E.Z.; Frolova, L.Y.; Kisselev, L.L.
Influence of individual domains of the translation termination factor eRF1 on induction of the GTPase activity of the translation termination factor eRF3 (2006), Mol. Biol., 40, 270-275.

No PubMed abstract available

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + H2O	GTPase activation due to C domain of the translation termination factor eRF1, which is bound with translation termination factor eRF3. As for the M and N domains, stimulation of eRF3 GTPase activity is more likely associated with the former, which is located in the large subunit along with the GTPase center of the ribosome, than with the latter, which is oriented towards the decoding center located in the small ribosomal subunit	Homo sapiens	GDP + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
translation termination factor eRF3	-	Homo sapiens

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Release 2023.1 (January 2023)