Any feedback?
Literature summary for 3.6.5.3 extracted from
- Opposite roles of domains 2+3 of Escherichia coli EF-Tu and Bacillus stearothermophilus EF-Tu in the regulation of EF-Tu GTPase activity (2005), Biochim. Biophys. Acta, 1752, 11-17.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | extodomain 2+3 stimulate the GTPase activity of ectodomain 1 | Geobacillus stearothermophilus | GDP + phosphate | - |
? |  |
| GTP + H2O | extodomain 2+3 suppress the GTPase activity of ectodomain 1 | Geobacillus stearothermophilus | GDP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EF-Tu | - |
Geobacillus stearothermophilus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 32 | - |
GTPase activity of domain 1 | Geobacillus stearothermophilus |
| 38 | - |
GTPase activity of domain 1 fused to domain 2+3 | Geobacillus stearothermophilus |
| 50 | - |
GTPase activity of domain 1 | Geobacillus stearothermophilus |
| 61 | - |
GTPase activity of domain 1 fused to domain 2+3 | Geobacillus stearothermophilus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| additional information | - |
domain 1 and domains 2+3 of both EF-Tu positively cooperate to heat-stabilize the GTPase center to attain optimal activity at alpha-helical regions of the G-domain | Geobacillus stearothermophilus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
