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BRENDA support

Literature summary for 3.6.5.3 extracted from

  • Focia, P.J.; Alam, H.; Lu, T.; Ramirez, U.D.; Freymann, D.M.
    Novel protein and Mg2+ configurations in the Mg2+ GDP complex of the SRP GTPase Ffh (2004), Proteins Struct. Funct. Bioinform., 54, 222-230.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the Mg2+-GDP complex of the Ffh NG-domain refined at 2.1 Å resolution Thermus aquaticus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ GTPase bound to Mg2+GDP reveals two new binding conformations. In the first the protein undergoes a conformational change that brings a conserved aspartate into its second coordination sphere. In the second, the magnesium coordination sphere is disrupted so that only five oxygen ligands are present Thermus aquaticus

Organism

Organism UniProt Comment Textmining
Thermus aquaticus
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
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Thermus aquaticus GDP + phosphate
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?

Synonyms

Synonyms Comment Organism
signal recognition particle GTPase Ffh
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Thermus aquaticus
SRP GTPase Ffh
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Thermus aquaticus