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Literature summary for 3.6.5.2 extracted from

  • Dobrin, S.E.; Fahrbach, S.E.
    Rho GTPase activity in the honey bee mushroom bodies is correlated with age and foraging experience (2012), J. Insect Physiol., 58, 228-234.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.5.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Apis mellifera
-
 GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Apis mellifera
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain Rho GTPase activation in the worker honey bee brain Apis mellifera
-
mushroom body a transient increase in Rac activity coupled with a transient decrease in RhoA activity occurs in honey bees with 4 days foraging experience compared with same-aged new foragers Apis mellifera
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Apis mellifera GDP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
Rac
-
 Apis mellifera
RhoA
-
 Apis mellifera
small, monomeric G protein
-
 Apis mellifera

General Information

General Information Comment Organism
evolution Rac and RhoA belong to the Rho family of GTPases, small monomeric G proteins Apis mellifera
physiological function Rac and RhoA belong to the small, monomeric G proteins of the Rho family of GTPases, that, when activated, initiate a signaling cascade that reorganizes the neuronal cytoskeleton. Rho GTPases regulate cellular morphogenesis through direct interactions with actin and microtubule-organizing proteins. Rho GTPases are cycling between the inactive GDP-bound and the active GTP-bound forms is controlled by guanine nucleotide exchange factors, GTPase activating proteins, and guanine nucleotide dissociation inhibitors Apis mellifera