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Literature summary for 3.6.5.2 extracted from

  • Fuchs, S.; Herzog, D.; Sumara, G.; Buechmann-Moller, S.; Civenni, G.; Wu, X.; Chrostek-Grashoff, A.; Suter, U.; Ricci, R.; Relvas, J.B.; Brakebusch, C.; Sommer, L.
    Stage-specific control of neural crest stem cell proliferation by the small Rho GTPases Cdc42 and Rac1 (2009), Cell Stem cell, 4, 236-247.
    View publication on PubMed
Search for more literature for 3.6.5.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus Rac1 and Cdc42 are not required for differentiation and migration of neural crest cells, but are essential for mitotic activity and cell-cycle control in neural crest cell target structures ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Mus musculus
-
neural crest cell line
-
 Mus musculus
-
neural crest-derived stem cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Mus musculus GDP + phosphate
-
 ?
additional information Rac1 and Cdc42 are not required for differentiation and migration of neural crest cells, but are essential for mitotic activity and cell-cycle control in neural crest cell target structures Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
Cdc42
-
 Mus musculus
Rac1
-
 Mus musculus