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Literature summary for 3.6.5.2 extracted from
- Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity (2004), Mol. Cell. Biol., 24, 7965-7975.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Homo sapiens | tuberous sclerosis complex TSC2 displays activity of a GTPase-activating protein specifically towards the small G protein Rheb and inhibits its ability to stimulate the mTOR signalling pathway | GDP + phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | tuberous sclerosis complex TSC2 displays activity of a GTPase-activating protein specifically towards the small G protein Rheb and inhibits its ability to stimulate the mTOR signalling pathway | Homo sapiens | GDP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Rheb | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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