KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1 | - |
GTP | G36 protein, unmodified | Homo sapiens | |
0.85 | - |
GTP | G36 protein phosphorylated by protein kinase M-like kinase | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | protein kinase K-like kinase phosphorylates G36 protein. The phosphorylation of G36 increases its Km for GTP by about 8fold without modification of Vmax. No significant modification after phosphorylation of G50 by protein kinase C or cAMP kinase | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | G36 with a MW of 36000 Da determined by SDS-PAGE can be Gialpha or Goalpha. G50 with a MW of 50000 Da determined by SDS-PAGE can be Gsalpha | Homo sapiens |