Any feedback?
Literature summary for 3.6.4.10 extracted from
- Temperature interactions of the molecular chaperone Hsc70 from the eurythermal marine goby Gillichthys mirabilis (2001), J. Exp. Biol., 204, 2675-2682.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| unfolded protein | reduced carboxymethylated alpha-lactalbumin, 0.08 mM, 28% stimulation above intrinsic activity | Gillichthys mirabilis |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Gillichthys mirabilis | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
x * 70000, immunoblot, two-dimensional SDS-PAGE | Gillichthys mirabilis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Gillichthys mirabilis | - |
ADP + phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gillichthys mirabilis | - |
marine gobi | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE-Sephacel, ATP-agarose | Gillichthys mirabilis |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skeletal muscle | white | Gillichthys mirabilis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Gillichthys mirabilis | ADP + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 70000, immunoblot, two-dimensional SDS-PAGE | Gillichthys mirabilis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Hsc70 | - |
Gillichthys mirabilis |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 10 | 45 | approx. 12fold increase in reaction rate between 10°C and 15°C, approx. 4fold increase in reaction rate between 25°C and 35°C | Gillichthys mirabilis |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | 63 | no loss of activity after 60 min | Gillichthys mirabilis |
| 65 | 80 | almost complete loss of activity after 60 min | Gillichthys mirabilis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
