Activating Compound | Comment | Organism | Structure |
---|---|---|---|
apo c | cytosolic precursor of cytochrome c | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0137 | - |
ATP | in absence of apo c | Bos taurus | |
0.0144 | - |
ATP | in presence of apo c | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Saccharomyces cerevisiae | 5829 | - |
cytosol | Hsp70 | Bos taurus | 5829 | - |
endoplasmic reticulum | - |
Saccharomyces cerevisiae | 5783 | - |
endoplasmic reticulum | Grp78 | Bos taurus | 5783 | - |
mitochondrial matrix | Hsp70 | Bos taurus | 5759 | - |
nucleus | hsc70 | Bos taurus | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
- |
Escherichia coli |
70000 | - |
gel filtration | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Escherichia coli | - |
ADP + phosphate | - |
? | |
ATP + H2O | Saccharomyces cerevisiae | - |
ADP + phosphate | - |
? | |
ATP + H2O | Bos taurus | - |
ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Escherichia coli | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Escherichia coli | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Saccharomyces cerevisiae | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000026 | - |
- |
Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Escherichia coli | ADP + phosphate | - |
? | |
ATP + H2O | - |
Saccharomyces cerevisiae | ADP + phosphate | - |
? | |
ATP + H2O | - |
Bos taurus | ADP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BiP | - |
Bos taurus |
DnaK | - |
Escherichia coli |
eukaryotic Hsc70 ATPase | - |
Saccharomyces cerevisiae |
eukaryotic Hsc70 ATPase | - |
Bos taurus |
Grp78 | - |
Bos taurus |
heat shock cognate protein | - |
Escherichia coli |
heat shock cognate protein | - |
Bos taurus |
Hsc70 | - |
Saccharomyces cerevisiae |
Hsc70 | - |
Bos taurus |
molecular chaperone GroEl | - |
Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0025 | - |
ATP | intrinsic rate | Bos taurus | |
0.00633 | - |
ATP | apo c stimulated rate | Bos taurus |