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Literature summary for 3.6.1.23 extracted from

  • Hemsworth, G.R.; Gonzalez-Pacanowska, D.; Wilson, K.S.
    On the catalytic mechanism of dimeric dUTPases (2013), Biochem. J., 456, 81-88.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Trypanosoma brucei

Crystallization (Commentary)

Crystallization (Comment) Organism
transition state analogue complexes in presence of dUMP, AlF3 and MgF3-. In the dimeric enzyme, the nucleophilic attack occurs on the beta-phosphate group Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei Q57ZH3
-
-
Trypanosoma brucei 927/4 Q57ZH3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dUTP + H2O
-
Trypanosoma brucei dUMP + diphosphate
-
?
dUTP + H2O
-
Trypanosoma brucei 927/4 dUMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
Tb927.7.5160
-
Trypanosoma brucei