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Literature summary for 3.6.1.1 extracted from

  • Lahti, R.; Salminen, T.; Latonen, S.; Heikinheimo, P.; Pohjanoksa, K.; Heinonen, J.
    Genetic engineering of Escherichia coli inorganic pyrophosphate Tyr55 and Tyr 141 are important for the structural integrity (1991), Eur. J. Biochem., 198, 293-297.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
Y117F same activity compared to wild type, thermostability as wild type Escherichia coli
Y141F 22% relative activity compared to wild type enzyme, decreased thermostability compared to wild type Escherichia coli
Y16F same activity compared to wild type, thermostability as wild type Escherichia coli
Y30F same activity compared to wild type, thermostability as wild type Escherichia coli
Y51F 64% relative activity compared to wild type enzyme, thermostability as wild type Escherichia coli
Y55F 7% relative activity compared to wild type enzyme, conformational change, thermostability as wild type Escherichia coli
Y57F same activity compared to wild type, thermostability as wild type Escherichia coli
Y77F same activity compared to wild type, thermostability as wild type Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O Escherichia coli
-
2 phosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O
-
Escherichia coli 2 phosphate
-
?