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Literature summary for 3.6.1.1 extracted from

  • Oliva, G.; Romero, I.; Ayala, G.; Barrios-Jacobo, I.; Celis, H.
    Characterization of the inorganic pyrophosphatase from the pathogenic bacterium Heliobacter pylori (2000), Arch. Microbiol., 174, 104-110.
    View publication on PubMed
Search for more literature for 3.6.1.1

Inhibitors

Inhibitors Comment Organism Structure
NaF
-
 Helicobacter pylori

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.09
-
 Mg-diphosphate
-
 Helicobacter pylori

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Helicobacter pylori 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ maximum activity Helicobacter pylori

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19100
-
 6 * 19100, SDS-PAGE Helicobacter pylori
103000
-
 SDS-PAGE Helicobacter pylori

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O Helicobacter pylori actual substrate is magnesium diphosphate or dimagnesium diphosphate 2 phosphate
-
 ?
diphosphate + H2O Helicobacter pylori 8823 actual substrate is magnesium diphosphate or dimagnesium diphosphate 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Helicobacter pylori
-
-
-
Helicobacter pylori 8823
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially Helicobacter pylori

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
141.7
-
-
 Helicobacter pylori

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O actual substrate is magnesium diphosphate or dimagnesium diphosphate Helicobacter pylori 2 phosphate
-
 ?
diphosphate + H2O high specificity Helicobacter pylori 2 phosphate
-
 ?
diphosphate + H2O diphosphate in form of Mg-diphosphate Helicobacter pylori 2 phosphate
-
 ?
diphosphate + H2O actual substrate is magnesium diphosphate or dimagnesium diphosphate Helicobacter pylori 8823 2 phosphate
-
 ?
diphosphate + H2O high specificity Helicobacter pylori 8823 2 phosphate
-
 ?
diphosphate + H2O diphosphate in form of Mg-diphosphate Helicobacter pylori 8823 2 phosphate
-
 ?

Subunits

Subunits Comment Organism
hexamer 6 * 19100, SDS-PAGE Helicobacter pylori

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Helicobacter pylori

pH Range

pH Minimum pH Maximum Comment Organism
5.5 10 no activity below 5.5, about 75% activity at pH 10 Helicobacter pylori