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Literature summary for 3.5.4.5 extracted from
- Identification and functional characterization of a novel cytidine deaminase in a gastropod abalone, Haliotis diversicolor supertexta (2009), Dev. Comp. Immunol., 33, 709-717.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Haliotis diversicolor supertexta |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | CDA is largely concentrated in the cytoplasm | Haliotis diversicolor supertexta | 5737 | - |
| nucleus | CDA is partially concentrated in the nuclei | Haliotis diversicolor supertexta | 5634 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | zinc-dependent enzyme | Haliotis diversicolor supertexta |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 16600 | - |
4 * 16600, calculated from amino acid sequence | Haliotis diversicolor supertexta |
| 20000 | - |
4 * 20000, SDS-PAGE | Haliotis diversicolor supertexta |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cytidine + H2O | Haliotis diversicolor supertexta | - |
uridine + NH3 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Haliotis diversicolor supertexta | C0IL37 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Haliotis diversicolor supertexta |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| digestive gland | - |
Haliotis diversicolor supertexta | - |
| gill | - |
Haliotis diversicolor supertexta | - |
| hemocyte | - |
Haliotis diversicolor supertexta | - |
| mantle | mantle margin | Haliotis diversicolor supertexta | - |
| muscle | foot muscle | Haliotis diversicolor supertexta | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cytidine + H2O | - |
Haliotis diversicolor supertexta | uridine + NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetramer | 4 * 20000, SDS-PAGE | Haliotis diversicolor supertexta |
| homotetramer | 4 * 16600, calculated from amino acid sequence | Haliotis diversicolor supertexta |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CDA | - |
Haliotis diversicolor supertexta |
| CDD | - |
Haliotis diversicolor supertexta |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Haliotis diversicolor supertexta | calculated from amino acid sequence | - |
7.3 |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Haliotis diversicolor supertexta | significant up-regulation of CDA is observed after lipopolysaccharide (3fold after 18 h) or polyriboinosinic polyribocytidylic acid challenge (4.5fold after 18 h) | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | CDA is involved in the immune response of gastropod abalone | Haliotis diversicolor supertexta |
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