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Literature summary for 3.5.4.4 extracted from

  • Pornbanlualap, S.; Chalopagorn, P.
    Adenosine deaminase from Streptomyces coelicolor: Recombinant expression, purification and characterization (2011), Protein Expr. Purif., 78, 167-173.
    View publication on PubMed
Search for more literature for 3.5.4.4

Inhibitors

Inhibitors Comment Organism Structure
2'-deoxycoformycin
-
 Streptomyces coelicolor
coformycin
-
 Streptomyces coelicolor

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.029
-
 adenosine 37°C, pH not specified in the publication Streptomyces coelicolor
0.56
-
 2'-deoxyadenosine 37°C, pH not specified in the publication Streptomyces coelicolor

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48400
-
 SDS-PAGE Streptomyces coelicolor
182000
-
 gel filtration Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine + H2O
-
 Streptomyces coelicolor 2'-deoxyinosine + NH3
-
 ?
adenosine + H2O
-
 Streptomyces coelicolor inosine + NH3
-
 ?

Subunits

Subunits Comment Organism
tetramer SDS-PAGE, 4 * 48400 Streptomyces coelicolor

Synonyms

Synonyms Comment Organism
adenosine deaminase
-
 Streptomyces coelicolor
SCO4901
-
 Streptomyces coelicolor

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
11.5
-
 adenosine 37°C, pH not specified in the publication Streptomyces coelicolor

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00000025
-
 coformycin 37°C, pH not specified in the publication Streptomyces coelicolor
0.0000034
-
 2'-deoxycoformycin 37°C, pH not specified in the publication Streptomyces coelicolor