Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aspirin | significantly decreases adenosine deaminase activity, the half-life of adenosine will be lengthened as a consequence of decreased adenosine deaminase activity | Oryctolagus cuniculus | |
erythro-9-(2-hydroxy-3-nonyl)-adenine | 0.1 mM concentration, ADA2 is practically unaffected; 0.1 mM concentration, complete and reversible inhibition | Oryctolagus cuniculus | |
isosorbide mononitrate | significantly decreases adenosine deaminase activity, the half-life of adenosine will be lengthened as a consequence of decreased adenosine deaminase activity | Oryctolagus cuniculus | |
metoprolol | significantly decreases adenosine deaminase activity, the half-life of adenosine will be lengthened as a consequence of decreased adenosine deaminase activity | Oryctolagus cuniculus | |
additional information | ADA1 activity is not changed significantly by aspirin, metoprolol, isosorbide mononitrate, and molsidominemolsidomine; molsidomine does not influence plasma adenosine deaminase activity significantly | Oryctolagus cuniculus | |
simvastatin | inhibits ADA1 activity by 46.7%; significantly decreases adenosine deaminase activity, the half-life of adenosine will be lengthened as a consequence of decreased ADA activity | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Oryctolagus cuniculus | 5737 | - |
extracellular | - |
Oryctolagus cuniculus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Oryctolagus cuniculus | - |
erythrocyte | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + H2O | - |
Oryctolagus cuniculus | inosine + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADA1 | - |
Oryctolagus cuniculus |
ADA2 | - |
Oryctolagus cuniculus |
adenosine deaminase | - |
Oryctolagus cuniculus |