Crystallization (Comment) | Organism |
---|---|
PDB ID 1UAQ, structure analysis and comparison to the quantum mechanical/molecular mechanical molecular dynamics simulation model, overview | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cytosine + H2O | Saccharomyces cerevisiae | - |
uracil + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | Q12178 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | - |
? | |
pyrimidin-2-one + H2O | stabilization of a transition-state analogue at the active site of cytosine deaminase with importance of proton transfer from the Zn hydroxide group to Glu64 during the nucleophilic attack, quantum mechanical/molecular mechanical molecular dynamics and free energy simulations, active site structure, overview | Saccharomyces cerevisiae | (4R)-hydroxyl-3,4-dihydropyrimidine + ? | - |
? |