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Literature summary for 3.5.4.1 extracted from
- Combined liposome-mediated cytosine deaminase gene therapy with radiation in killing rectal cancer cells and xenografts in athymic mice (2005), Clin. Cancer Res., 11, 3574-3578.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | efficiency of liposome-mediated cytosine deaminase suicide gene therapy can be improved by radiation. With HR-8348 tumor xenograft model, tumor volume is inhibited by 81.5%, 48.5%, and 37.5%, in the combined enzyme/5-fluorocytosine with radiation group, enzyme/5-fluorocytosine group and radiation group, and the wet weight of tumor is decreased by 80%, 41.7%, and 37.7%, resp. | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
recombinant enzyme | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
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