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Literature summary for 3.5.4.1 extracted from
- Chemical modification of cytosine deaminase from Aspergillus fumigatus (1998), J. Microbiol., 36, 39-42.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| diethyldicarbonate | 1.0 mM, relative activity 102% | Aspergillus fumigatus |  |
| ethylacetoimidate | - |
Chromobacterium violaceum | |
| ethylacetoimidate | 1.0 mM, relative activity 101% | Aspergillus fumigatus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Aspergillus fumigatus | |
| Chloramine T | - |
Aspergillus fumigatus | |
| Chloramine T | - |
Chromobacterium violaceum | |
| Cu2+ | - |
Aspergillus fumigatus | |
| Cu2+ | - |
Chromobacterium violaceum | |
| Cu2+ | - |
Escherichia coli | |
| Cu2+ | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| Cu2+ | - |
Serratia marcescens | |
| Fe2+ | - |
Aspergillus fumigatus | |
| Fe2+ | - |
Chromobacterium violaceum | |
| Hg2+ | - |
Aspergillus fumigatus | |
| Hg2+ | - |
Chromobacterium violaceum | |
| Hg2+ | - |
Escherichia coli | |
| Hg2+ | - |
Serratia marcescens | |
| N-bromosuccinimide | - |
Aspergillus fumigatus | |
| o-phenanthroline | - |
Aspergillus fumigatus | |
| o-phenanthroline | - |
Chromobacterium violaceum | |
| o-phenanthroline | - |
Escherichia coli | |
| o-phenanthroline | - |
Saccharomyces cerevisiae | |
| p-chloromercuribenzoic acid | - |
Aspergillus fumigatus | |
| p-chloromercuribenzoic acid | - |
Chromobacterium violaceum | |
| p-chloromercuribenzoic acid | - |
Escherichia coli | |
| Pb2+ | - |
Aspergillus fumigatus | |
| phenylmethylsulfonyl fluoride | - |
Aspergillus fumigatus | |
| phenylmethylsulfonyl fluoride | - |
Chromobacterium violaceum | |
| pyridoxal-5'-phosphate | - |
Aspergillus fumigatus | |
| pyridoxal-5'-phosphate | - |
Chromobacterium violaceum | |
| UTP | - |
Aspergillus fumigatus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Chromobacterium violaceum | - |
- |
| extracellular | - |
Aspergillus fumigatus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
SDS-PAGE | Aspergillus fumigatus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cytosine + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Escherichia coli | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Saccharomyces cerevisiae | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Chromobacterium violaceum | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Serratia marcescens | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Aspergillus fumigatus | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Pseudomonas chlororaphis subsp. aureofaciens | - |
uracil + NH3 | - |
? | |
| cytosine + H2O | Chromobacterium violaceum YK 391 | - |
uracil + NH3 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus fumigatus | - |
- |
- |
| Chromobacterium violaceum | - |
YK 391 | - |
| Chromobacterium violaceum YK 391 | - |
YK 391 | - |
| Escherichia coli | - |
- |
- |
| Pseudomonas chlororaphis subsp. aureofaciens | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
| Serratia marcescens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
- |
Escherichia coli |
- |
Serratia marcescens |
- |
Aspergillus fumigatus |
- |
Pseudomonas chlororaphis subsp. aureofaciens |
| partially | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-fluorocytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 5-fluorouracil + NH3 | - |
? | |
| 5-fluorocytosine + H2O | - |
Escherichia coli | 5-fluorouracil + NH3 | - |
? | |
| 5-fluorocytosine + H2O | - |
Saccharomyces cerevisiae | 5-fluorouracil + NH3 | - |
? | |
| 5-fluorocytosine + H2O | - |
Chromobacterium violaceum | 5-fluorouracil + NH3 | - |
? | |
| 5-fluorocytosine + H2O | - |
Aspergillus fumigatus | 5-fluorouracil + NH3 | - |
? | |
| 5-fluorocytosine + H2O | - |
Chromobacterium violaceum YK 391 | 5-fluorouracil + NH3 | - |
? | |
| 5-methylcytosine + H2O | - |
Saccharomyces cerevisiae | thymine + NH3 | - |
? | |
| 5-methylcytosine + H2O | - |
Chromobacterium violaceum | thymine + NH3 | - |
? | |
| 5-methylcytosine + H2O | - |
Aspergillus fumigatus | thymine + NH3 | - |
? | |
| 5-methylcytosine + H2O | - |
Pseudomonas chlororaphis subsp. aureofaciens | thymine + NH3 | - |
? | |
| 5-methylcytosine + H2O | - |
Chromobacterium violaceum YK 391 | thymine + NH3 | - |
? | |
| cytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Escherichia coli | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Chromobacterium violaceum | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Serratia marcescens | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Aspergillus fumigatus | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Pseudomonas chlororaphis subsp. aureofaciens | uracil + NH3 | - |
? | |
| cytosine + H2O | - |
Chromobacterium violaceum YK 391 | uracil + NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 32000, SDS-PAGE | Aspergillus fumigatus |
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