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Literature summary for 3.5.3.18 extracted from
- Dimethylarginine dimethylaminohydrolase inhibition and asymmetric dimethylarginine accumulation contribute to endothelial dysfunction in rats exposed to glycosylated protein: Effects of aminoguanidine (2006), Atherosclerosis, 190, 53-61.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | DDAH activity and elevated endogenous asymmetric dimethylarginine is implicated in endothelial dysfunction exposed to glycosylated bovine serum albumin, aminoguanidine can protect endothelium against injury induced by glycosylated bovine serum albumin both in vitro and in vivo | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta endothelium | - |
Rattus norvegicus | - |
| aorta thoracica | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DDAH | - |
Rattus norvegicus |
| dimethylarginine dimethylaminohydrolase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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