Literature summary for 3.5.3.11 extracted from

Bernstein, H.G.; Stich, C.; Jaeger, K.; Dobrowolny, H.; Wick, M.; Steiner, J.; Veh, R.; Bogerts, B.; Laube, G.
Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders (2012), Neuropharmacology, 62, 237-246.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hippocampus	agmatinase protein is detected in a subset of hippocampal interneurons. The protein is localized to perikarya, neurites and putative nerve endings contacting hippocampal pyramidal neurons and dentate gyrus granule cells. The number and the numerical density of agmatinase-immunopositive cell bodies are strongly elevated in depressive patients	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
agmatinase	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	agmatinase expression is up-regulated in hippocampal interneurons of patients with mood disorders	up

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Release 2023.1 (January 2023)