Protein Variants | Comment | Organism |
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additional information | analysis of 516 mutated enzymes that acquired the ceftazidime-hydrolyzing activity, and identification of twelve positions with single amino acid substitutions, co-localized at the active-site pocket area. single amino acid substitutions are found at positions C89, N136, L162, R164, E166, L169, N170, T171, A172, P174, D176, D179. All substitutions cause a congruent effect, expanding the space in a conserved structure called the omega loop, which in turn increased flexibility at the active site | Burkholderia thailandensis |
Organism | UniProt | Comment | Textmining |
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Burkholderia thailandensis | - |
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Synonyms | Comment | Organism |
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PenA | - |
Burkholderia thailandensis |