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Literature summary for 3.5.2.6 extracted from

  • Ahmed, A.M.; Shimamoto, T.
    Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC beta -lactamase, CMY-37 (2008), Int. J. Antimicrob. Agents, 32, 256-261.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli TG1 Citrobacter freundii

Protein Variants

Protein Variants Comment Organism
L316I substitution is located within the R2 loop that is considered the hotspot region responsible for the extended substrate spectrum in class C beta-lactamases Citrobacter freundii

Inhibitors

Inhibitors Comment Organism Structure
additional information Citrobacter freundii has a cefepime and cefpirome resistance Citrobacter freundii

Organism

Organism UniProt Comment Textmining
Citrobacter freundii
-
-
-
Citrobacter freundii 4306
-
-
-

Synonyms

Synonyms Comment Organism
AmpC
-
Citrobacter freundii
beta-lactamase
-
Citrobacter freundii
CMY-37
-
Citrobacter freundii

pI Value

Organism Comment pI Value Maximum pI Value
Citrobacter freundii about
-
9