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Literature summary for 3.5.2.6 extracted from

  • Bhattacharjee, A.; Sen, M.R.; Prakash, P.; Anupurba, S.
    Role of beta-lactamase inhibitors in enterobacterial isolates producing extended-spectrum beta-lactamases (2008), J. Antimicrob. Chemother., 61, 309-314.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cefotaxime
-
Escherichia coli
cefotaxime
-
Klebsiella sp.
cefotaxime
-
Proteus mirabilis
cefpodoxime
-
Escherichia coli
cefpodoxime
-
Klebsiella sp.
cefpodoxime
-
Proteus mirabilis
ceftriaxone
-
Escherichia coli
ceftriaxone
-
Klebsiella sp.
ceftriaxone
-
Proteus mirabilis
clavulanic acid shows 8fold reduction with clavulanic acid when combined with ceftriaxone, cefpodoxime and cefotaxime Escherichia coli
clavulanic acid shows 8fold reduction with clavulanic acid when combined with ceftriaxone, cefpodoxime and cefotaxime Klebsiella sp.
clavulanic acid shows 8fold reduction with clavulanic acid when combined with ceftriaxone, cefpodoxime and cefotaxime Proteus mirabilis
additional information not inhibited by ceftazidime and aztreonam Escherichia coli
additional information not inhibited by ceftazidime and aztreonam Klebsiella sp.
additional information not inhibited by ceftazidime and aztreonam Proteus mirabilis
Sulbactam shows 8fold reduction of activity with sulbactam when combined with ceftriaxone, cefpodoxime and cefotaxime Escherichia coli
Sulbactam shows 8fold reduction of activity with sulbactam when combined with ceftriaxone, cefpodoxime and cefotaxime Klebsiella sp.
Sulbactam shows 8fold reduction of activity with sulbactam when combined with ceftriaxone, cefpodoxime and cefotaxime Proteus mirabilis

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Klebsiella sp.
-
-
-
Proteus mirabilis
-
-
-

Synonyms

Synonyms Comment Organism
AmpC
-
Escherichia coli
AmpC
-
Proteus mirabilis
AmpC
-
Klebsiella sp.
ESBL
-
Escherichia coli
ESBL
-
Proteus mirabilis
ESBL
-
Klebsiella sp.
extended-spectrum beta-lactamase
-
Escherichia coli
extended-spectrum beta-lactamase
-
Proteus mirabilis
extended-spectrum beta-lactamase
-
Klebsiella sp.