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Literature summary for 3.5.2.6 extracted from

  • Sanschagrin, F.; Levesque, R.C.
    A specific peptide inhibitor of the class B metallo-beta-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display (2005), J. Antimicrob. Chemother., 55, 252-255.
    View publication on PubMed
Search for more literature for 3.5.2.6

Inhibitors

Inhibitors Comment Organism Structure
Cys-Val-His-Ser-Pro-Asn-Arg-Glu-Cys mixed inhibition Stenotrophomonas maltophilia
additional information no inhibition: Cys-Val-His-Ser-Pro-Asn-Arg-Glu-Cys Stenotrophomonas maltophilia

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.015
-
 nitrocefin 30°C, pH 8.0 Stenotrophomonas maltophilia

Organism

Organism UniProt Comment Textmining
Stenotrophomonas maltophilia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nitrocefin + H2O
-
 Stenotrophomonas maltophilia (2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?

Synonyms

Synonyms Comment Organism
class B metallo-beta-lactamase L-1
-
 Stenotrophomonas maltophilia

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
24
-
 nitrocefin 30°C, pH 8.0 Stenotrophomonas maltophilia

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.009
-
 Cys-Val-His-Ser-Pro-Asn-Arg-Glu-Cys 30°C, pH 8.0, uncompetitive Stenotrophomonas maltophilia
0.016
-
 Cys-Val-His-Ser-Pro-Asn-Arg-Glu-Cys 30°C, pH 8.0, competitive Stenotrophomonas maltophilia