Cloned (Comment) | Organism |
---|---|
PdfA is cloned and overepressed in Escherichia coli | Legionella pneumophila |
PdfB is cloned and overepressed in Escherichia coli | Legionella pneumophila |
PdfC is cloned and overepressed in Escherichia coli | Legionella pneumophila |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
actinonin | - |
Legionella pneumophila | |
BB-3497 | - |
Legionella pneumophila |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
formyl-Met-Ala | Zn2+ PdfC | Legionella pneumophila | |
0.3 | - |
formyl-Met-Ala-Ser | Ni2+ PdB | Legionella pneumophila | |
0.34 | - |
formyl-Met-Ala-Lys-Tyr | Zn2+ PdB | Legionella pneumophila | |
0.35 | - |
formyl-Met-Ala | Ni2+ PdC | Legionella pneumophila | |
1.3 | - |
formyl-Met-Ala-Lys-Tyr | Ni2+ PdB | Legionella pneumophila | |
1.4 | - |
formyl-Met-Ala-Lys-Tyr | Zn2+ PdfB | Legionella pneumophila | |
1.5 | - |
formyl-Met-Ala | Ni2+ PdB | Legionella pneumophila | |
2.1 | - |
formyl-Met-Ala-Lys-Tyr | Ni2+ PdC | Legionella pneumophila | |
2.4 | - |
formyl-Met-Ala-Ser | Ni2+ PdC | Legionella pneumophila | |
2.7 | - |
formyl-Met-Ala | Zn2+ PdfB | Legionella pneumophila | |
3.8 | - |
formyl-Met-Ala-Lys-Tyr | Zn2+ PdfC | Legionella pneumophila | |
6.1 | - |
formyl-Met-Ala-Lys-Tyr | Zn2+ PdfA | Legionella pneumophila | |
7.6 | - |
formyl-Met-Ala-Lys-Tyr | Ni2+ PdA | Legionella pneumophila | |
14 | - |
formyl-Met-Ala | Zn2+ PdfA | Legionella pneumophila | |
20 | - |
formyl-Met-Ala-Ser | Zn2+ PdA | Legionella pneumophila | |
21 | - |
formyl-Met-Ala-Ser | Ni2+ PdA | Legionella pneumophila | |
28 | - |
formyl-Met-Ala | Ni2+ PdA | Legionella pneumophila |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ni2+ | PdfA with Zn2+ substituted is much less active than the Ni2+ forms of the enzyme | Legionella pneumophila | |
Ni2+ | PdfB with Zn2+ substituted is much less active than the Ni2+ forms of the enzyme | Legionella pneumophila | |
Ni2+ | PdfC with Zn2+ substituted is as active as the Ni+ form for the fMA substrate and exhibits substrate specificity different from that of Ni2+ PdfC | Legionella pneumophila | |
Zn2+ | PdfA with Zn2+ substituted is much less active than the Ni2+ forms of the enzyme | Legionella pneumophila | |
Zn2+ | PdfB with Zn2+ substituted is much less active than the Ni2+ forms of the enzyme | Legionella pneumophila | |
Zn2+ | PdfC with Zn2+ substituted is as active as the Ni+ form for the fMA substrate and exhibits substrate specificity different from that of Ni2+ PdfC | Legionella pneumophila |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Legionella pneumophila | - |
- |
- |
Legionella pneumophila Philadelphia 1 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant PdfA | Legionella pneumophila |
recombinant PdfB | Legionella pneumophila |
recombinant PdfC | Legionella pneumophila |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formyl-Met-Ala + H2O | - |
Legionella pneumophila | formate + Met-Ala | - |
? | |
formyl-Met-Ala + H2O | - |
Legionella pneumophila Philadelphia 1 | formate + Met-Ala | - |
? | |
formyl-Met-Ala-Lys-Tyr + H2O | - |
Legionella pneumophila | formate + Met-Ala-Lys-Tyr | - |
? | |
formyl-Met-Ala-Lys-Tyr + H2O | - |
Legionella pneumophila Philadelphia 1 | formate + Met-Ala-Lys-Tyr | - |
? | |
formyl-Met-Ala-Ser + H2O | - |
Legionella pneumophila | formate + Met-Ala-Ser | - |
? | |
formyl-Met-Ala-Ser + H2O | - |
Legionella pneumophila Philadelphia 1 | formate + Met-Ala-Ser | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PdfA | - |
Legionella pneumophila |
PdfB | - |
Legionella pneumophila |
PdfC | - |
Legionella pneumophila |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00014 | - |
BB-3497 | Zn2+ PdfC | Legionella pneumophila | |
0.00015 | - |
actinonin | Ni2+ PdfB | Legionella pneumophila | |
0.000203 | - |
BB-3497 | Ni2+ PdfB | Legionella pneumophila | |
0.000281 | - |
actinonin | Zn2+ PdC | Legionella pneumophila | |
0.00058 | - |
actinonin | Ni2+ PdC | Legionella pneumophila | |
0.00094 | - |
BB-3497 | Ni2+ PdfA | Legionella pneumophila | |
0.0012 | - |
actinonin | Ni2+ PdfA | Legionella pneumophila | |
0.0016 | - |
BB-3497 | Ni2+ PdfC | Legionella pneumophila |