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Literature summary for 3.5.1.5 extracted from

  • Wassermann, G.E.; Olivera-Severo, D.; Uberti, A.F.; Carlini, C.R.
    Helicobacter pylori urease activates blood platelets through a lipoxygenase-mediated pathway (2010), J. Cell. Mol. Med., 14, 2025-2034.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.5

Cloned(Commentary)

Cloned (Comment) Organism
recombinantly expressed in Escherichia coli Helicobacter pylori

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 SDS-PAGE, two major bands at 30 kDa and 60 kDa Helicobacter pylori
60000
-
 SDS-PAGE, two major bands at 30 kDa and 60 kDa Helicobacter pylori

Organism

Organism UniProt Comment Textmining
Helicobacter pylori
-
-
-

Purification (Commentary)

Purification (Comment) Organism
using ammonium sulfate precipitation, dialysis, and anion exchange chromatography Helicobacter pylori

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
HPU
-
 Helicobacter pylori
urease
-
 Helicobacter pylori

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Helicobacter pylori

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Helicobacter pylori

General Information

General Information Comment Organism
physiological function effects of urease added to rabbit platelets are assessed turbidimetrically. Fluorescein-labelled HPU bound to platelets but not to erythrocytes. HPU induces aggregation of rabbit platelets accompanied by ATP secretion. No correlation is found between platelet activation and ureolytic activity of HPU Helicobacter pylori