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Literature summary for 3.5.1.38 extracted from

  • Holcenberg, J.S.; Teller, D.C.
    Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A (1976), J. Biol. Chem., 251, 5375-5380.
    View publication on PubMed
Search for more literature for 3.5.1.38

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 4 * 36000, sedimentation equilibrium analysis in the presence of guanidine HCl, amino acid analysis Pseudomonas sp.
140000
-
 sedimentation equilibrium analysis Pseudomonas sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-asparagine + H2O Pseudomonas sp.
-
 L-aspartate + NH3
-
 ?
L-asparagine + H2O Pseudomonas sp. 7A
-
 L-aspartate + NH3
-
 ?
L-glutamine + H2O Pseudomonas sp. higher activity for glutaminase than for asparaginase L-glutamate + NH3
-
 ?
L-glutamine + H2O Pseudomonas sp. 7A higher activity for glutaminase than for asparaginase L-glutamate + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. 7A
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity Pseudomonas sp.

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Pseudomonas sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
100
-
 for L-asparagine Pseudomonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-diazo-4-oxo-L-norvaline + H2O
-
 Pseudomonas sp. ?
-
 ?
5-diazo-4-oxo-L-norvaline + H2O
-
 Pseudomonas sp. 7A ?
-
 ?
L-asparagine + H2O
-
 Pseudomonas sp. L-aspartate + NH3
-
 ?
L-asparagine + H2O
-
 Pseudomonas sp. 7A L-aspartate + NH3
-
 ?
L-glutamine + H2O higher activity for glutaminase than for asparaginase Pseudomonas sp. L-glutamate + NH3
-
 ?
L-glutamine + H2O higher activity for glutaminase than for asparaginase Pseudomonas sp. 7A L-glutamate + NH3
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 36000, sedimentation equilibrium analysis in the presence of guanidine HCl, amino acid analysis Pseudomonas sp.