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Literature summary for 3.5.1.26 extracted from

  • Park, H.; Vettese-Dadey, M.; Aronson, N.N.
    Glycosylation and phosphorylation of lysosomal glycosylasparaginase (1996), Arch. Biochem. Biophys., 328, 73-77.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
N308D less than 10% of wild-type activity, misprocessing of precursor Homo sapiens
N38D 30% of wild-type activity, proper processing to its mature lysosomal form Homo sapiens
T310A less than 10% of wild-type activity, more properly cleaved form than N308D Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein mannose-glycosyl groups at N38, T310 and N308 Homo sapiens
phosphoprotein phosphate on high-mannose type glycosyl groups Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta cDNA from placenta Homo sapiens
-