Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetate | no inhibition | Candida albicans | |
fructose-6-phosphate | 40 mM, 75% inhibition | Candida albicans | |
glucosamine 6-phosphate | competitive | Candida albicans | |
UDP-N-acetylglucosamine | 10 mM, 35% inhibition | Candida albicans | |
UTP | 7.5 mM, 21% inhibition | Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | Candida albicans | enzyme of the N-acetylglucosamine pathway | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | Candida albicans | inducible enzyme, trichodermin and lomofungin inhibit induction of the enzyme | D-glucosamine 6-phosphate + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Storage Stability | Organism |
---|---|
4°C, 100 mM Tris/HCl, pH 7.2, stable for 1 week | Candida albicans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | - |
Candida albicans | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | enzyme of the N-acetylglucosamine pathway | Candida albicans | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | inducible enzyme, trichodermin and lomofungin inhibit induction of the enzyme | Candida albicans | D-glucosamine 6-phosphate + acetate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Candida albicans |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 9.5 | more than 90% of maximal activity below pH 9.5 and above pH 7.0 | Candida albicans |