Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.11 extracted from

  • Basso, A.; Ebert, C.; Gardossi, L.; Linda, P.; Phuong, T.T.; Zhu, M.; Wessjohann, L.
    Penicillin G amidase-catalysed hydrolysis of phenylacetic hydrazides on a solid phase: A new route to enzyme-cleavable linkers (2005), Adv. Synth. Catal., 347, 963-966.
No PubMed abstract available

Application

Application Comment Organism
synthesis hydrolysis of phenylacetic hydrazide compounds syntesized on PEGA1900 and PEGA+ copolymers of acrylamide and ethylene glycol by enzyme diffusing into the polymer. Use in specific cleavage of linkers Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
additional information no product inhibition by hydrazine Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
commercial preparation, penicillin G amidase, Fluka
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenylacetamide + H2O
-
Escherichia coli phenylacetate + NH3
-
?
phenylacetic hydrazide + H2O
-
Escherichia coli phenylacetate + hydrazine
-
?