Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | ADAM9 does not respond to stimulation with phorbol esters, calcium ionophore or phosphatase inhibitors | Mus musculus |
Cloned (Comment) | Organism |
---|---|
expression in COS-7 cell | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
batimastat | - |
Mus musculus | |
GM6001 | hydroxamate inhibitor | Mus musculus | |
GW280264X | - |
Mus musculus | |
marimastat | - |
Mus musculus | |
additional information | not inhibitory: up to 20 nM of TIMP-1 or -2 | Mus musculus | |
TAPI-2 | hydroxamate inhibitor | Mus musculus | |
TIMP-3 | i.e. tissue inhibitor of metalloproteinases-3, inhibition at 10 nM | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q61072 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryonic fibroblast cell line | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ephrin receptor B4 + H2O | - |
Mus musculus | ? | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00005 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | batimastat | |
0.00013 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | marimastat | |
0.00048 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | GW280264X | |
0.00072 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | GM6001 | |
0.0135 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | TAPI-2 |