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Literature summary for 3.4.24.B9 extracted from

  • Asai, M.; Hattori, C.; Szabo, B.; Sasagawa, N.; Maruyama, K.; Tanuma, S.I.; Ishiura, S.
    Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase (2003), Biochem. Biophys. Res. Commun., 301, 231-235.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS-7 cells and in human glioblastoma A172 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane anchored on the cell surface Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amyloid precursor protein + H2O Homo sapiens enzyme shows alpha-secretase activity, the alpha-secretase might be composed of several ADAM enzymes in a complexe ?
-
?
proteins + H2O Homo sapiens
-
peptides
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-172 cell
-
Homo sapiens
-
brain
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid precursor protein + H2O enzyme shows alpha-secretase activity Homo sapiens ?
-
?
amyloid precursor protein + H2O enzyme shows alpha-secretase activity, the alpha-secretase might be composed of several ADAM enzymes in a complexe Homo sapiens ?
-
?
proteins + H2O
-
Homo sapiens peptides
-
?

Synonyms

Synonyms Comment Organism
ADAM9
-
Homo sapiens
M12.209 Merops-ID Homo sapiens