Any feedback?
Literature summary for 3.4.24.75 extracted from
- Anti-staphylococcal activities of lysostaphin and LytM catalytic domain (2012), BMC Microbiol., 12, 97.
General Stability
| General Stability | Organism |
|---|---|
| lysostaphin degrades Staphylococcus aureus cell walls inefficiently in low conductivity buffers (10-50 mS/cm) | Staphylococcus simulans |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | contains zinc | Staphylococcus simulans |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| peptidoglycan + H2O | Staphylococcus simulans | the enzyme cleaves pentaglycine crossbridges of Staphylococcus aureus peptidoglycan | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus simulans | P10547 | biovar Staphylococcus simulans staphylolyticus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| peptidoglycan + H2O | the enzyme cleaves pentaglycine crossbridges of Staphylococcus aureus peptidoglycan | Staphylococcus simulans | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Lss | - |
Staphylococcus simulans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9 | lysostaphin is marginally effective at pH 6.0 (50 mM phosphate buffer), but becomes much more active at pH 7.0. A further pH increase to the range between 7.0 and 9.0 (50 mM Tris-HCl) has little effect on the activity of lysostaphin | Staphylococcus simulans |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
