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Literature summary for 3.4.24.75 extracted from

  • Huang, C.; Hsu, J.; Chung, P.; ChengWINSTON, T.; Jiang, Y.; Ju, Y.
    Site-specific N-glycosylation of caprine lysostaphin restricts its bacteriolytic activity toward Staphylococcus aureus (2013), Anim. Biotechnol., 24, 129-147.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CMEC-08-D cells Staphylococcus simulans

Protein Variants

Protein Variants Comment Organism
N125Q the mutant possesses staphylolytic activity Staphylococcus simulans
N232Q the mutant lacks staphylolytic activity Staphylococcus simulans

Organism

Organism UniProt Comment Textmining
Staphylococcus simulans P10547
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein Asn125 is the exact glycosylation site of lysostaphin expressed in CMEC-08-D cells. N-glycosylation at Asn125 of lysostaphin decreases lysostaphin bacteriolytic activity but does not affect its binding ability to Staphylococcus aureus Staphylococcus simulans

Synonyms

Synonyms Comment Organism
LYS
-
Staphylococcus simulans