Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | IDE colocalizes with retinoblastoma tumor suppressor protein in cancer cells, overview. The amount of retinoblastoma tumor suppressor protein-IDE complex seems to be lower in Hep-G2 cells versus MCF-7 cells with increased nuclear localization, overview | Homo sapiens | 5737 | - |
additional information | interplay between retinoblastoma tumor suppressor protein and IDE within the proteasome that may have important growth-regulatory consequences | Homo sapiens | - |
- |
nucleus | IDE colocalizes with retinoblastoma tumor suppressor protein in cancer cells, overview. The amount of retinoblastoma tumor suppressor protein-IDE complex seems to be lower in Hep-G2 cells versus MCF-7 cells with increased nuclear localization, overview | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
isolation of the IDE/proteasomal complex from MCF-7 cells and HepG2 cells, IDE copurifies with the retinoblastoma tumor suppressor protein, overview | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | hepatoma cells | Homo sapiens | - |
MCF-7 cell | breast cancer cells | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
IDE | - |
Homo sapiens |
Insulin-degrading enzyme | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | interplay between retinoblastoma tumor suppressor protein and IDE within the proteasome that may have important growth-regulatory consequences | Homo sapiens |