Literature summary for 3.4.24.56 extracted from

Bernstein, H.G.; Lendeckel, U.; Bukowska, A.; Ansorge, S.; Ernst, T.; Stauch, R.; Truebner, K.; Steiner, J.; Dobrowolny, H.; Bogerts, B.
Regional and cellular distribution patterns of insulin-degrading enzyme in the adult human brain and pituitary (2008), J. Chem. Neuroanat., 35, 216-224.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
additional information	cellular distribution patterns in different tissues and brain regions, immunohistochemic analysis, overview	Homo sapiens	-	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	zinc metalloprotease	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
110000	-	1 * 110000	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood vessel	-	Homo sapiens	-
brain	post-mortal brains, regional and cellular distribution pattern, immunohistochemic analysis, overview	Homo sapiens	-
brain cortex	-	Homo sapiens	-
brain stem	-	Homo sapiens	-
cerebellum	-	Homo sapiens	-
choroid plexus	-	Homo sapiens	-
endothelial cell	blood vessel	Homo sapiens	-
hippocampus	-	Homo sapiens	-
neuron	-	Homo sapiens	-
oligodendrocyte	-	Homo sapiens	-
pituitary gland	post-mortal samples, regional and cellular distribution pattern, immunohistochemic analysis, overview	Homo sapiens	-

Subunits

Subunits	Comment	Organism
monomer	1 * 110000	Homo sapiens
More	the enzyme is probably part of a multienzyme complex and co-isolates with the multicatalytic proteinase	Homo sapiens

Synonyms

Synonyms	Comment	Organism
IDE	-	Homo sapiens
Insulin-degrading enzyme	-	Homo sapiens

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Release 2023.1 (January 2023)