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BRENDA support

Literature summary for 3.4.24.56 extracted from

  • Kim, S.; Lapham, A.N.; Freedman, C.G.; Reed, T.L.; Schmidt, W.K.
    Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme (2005), J. Biol. Chem., 280, 27481-27490.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information heterologous expression in Saccharomyces cerevisiae, enzyme can promote the in vivo production of yeast a-factor mating pheromone, but cannot substitue for other fuctions of yeast Axl1p. Enzyme requires an intact C-terminus for optimal activity Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
exprsssion in Sacchaoromyces cerevisiae
-