General Stability | Organism |
---|---|
repeated freezing and thawing inactivates | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
4 * 37000, human, SDS-PAGE of denatured enzyme | Homo sapiens |
150000 | 160000 | human, gel chromatography, gel electrophoresis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-40°C, neutral pH, stable for a long time | Homo sapiens |
4°C, neutral pH, stable for several days but specific activity decreases | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Insulin + H2O | specific for insulin | Homo sapiens | Hydrolyzed insulin | degradation products are smaller than the A-chain of insulin | ? | |
additional information | fructose 1,6-bisphosphatase | Homo sapiens | ? | - |
? | |
additional information | hexosephosphate isomerase | Homo sapiens | ? | - |
? | |
additional information | aldolase | Homo sapiens | ? | - |
? | |
additional information | no inactivation of: lactate dehydrogenase | Homo sapiens | ? | - |
? | |
additional information | thyroid-stimulating hormone | Homo sapiens | ? | - |
? | |
additional information | prolactin | Homo sapiens | ? | - |
? | |
additional information | hexokinase | Homo sapiens | ? | - |
? | |
additional information | not: growth hormone | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 37000, human, SDS-PAGE of denatured enzyme | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
40 | - |
irreversible inactivation and denaturation | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pI: 5.8 | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5.5 | 9 | unstable below pH 5.5 and above pH 9.0 | Homo sapiens |