Protein Variants | Comment | Organism |
---|---|---|
additional information | preparation of biotin-labeled mouse meprins | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | metalloprotease | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus BALB/c | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the enzyme is highly glycosylated | Mus musculus |
Purification (Comment) | Organism |
---|---|
isolation of meprins from the mouse kidneys by immunoaffinity chromatography using mannan-binding protein resin | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Mus musculus | - |
additional information | co-localization of the enzyme with serum-type mannan-binding protein and C3b on both the cortex and the medulla in the renal I/R-operated mouse kidney, overview | Mus musculus | - |
renal proximal tubule | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
meprin alpha | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | role of interaction of mannan-binding protein with meprins at the initial step of complement activation in ischemia/reperfusion injury to mouse kidney. Co-localization of the enzyme with serum-type mannan-binding protein and C3b on both the cortex and the medulla in the renal I/R-operated mouse kidney | Mus musculus |
physiological function | serum-type mannan-binding protein interacts with meprins in vivo in the I/R-operated mouse kidney and initiates the complement activation through the interaction with meprins in vitro, overview | Mus musculus |