Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | amastatin, arphamenine A, and bestatin have no effect on cathepsin H | Bos taurus | |
additional information | amastatin, arphamenine A, and bestatin have no effect on cathepsin H | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
secretory vesicle | - |
Mus musculus | 99503 | - |
secretory vesicle | - |
Bos taurus | 99503 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
x * 28000, SDS-PAGE | Mus musculus |
28000 | - |
x * 28000, SDS-PAGE | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal medulla | - |
Bos taurus | - |
brain | - |
Mus musculus | - |
chromaffin cell | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Arg-7-amido-4-methylcoumarin + H2O | best substrate | Mus musculus | L-Arg + 7-amino-4-methylcoumarin | - |
? | |
L-Arg-7-amido-4-methylcoumarin + H2O | best substrate | Bos taurus | L-Arg + 7-amino-4-methylcoumarin | - |
? | |
L-Lys-7-amido-4-methylcoumarin + H2O | best substrate | Mus musculus | L-Lys + 7-amino-4-methylcoumarin | - |
? | |
L-Lys-7-amido-4-methylcoumarin + H2O | best substrate | Bos taurus | L-Lys + 7-amino-4-methylcoumarin | - |
? | |
Lys-Arg-(Met)enkephalin + H2O | - |
Mus musculus | Lys-Arg + (Met)enkephalin | - |
? | |
Lys-Arg-(Met)enkephalin + H2O | - |
Bos taurus | Lys-Arg + (Met)enkephalin | - |
? | |
Lys-Lys-(Met)enkephalin + H2O | - |
Mus musculus | Lys-Lys + (Met)enkephalin | - |
? | |
Lys-Lys-(Met)enkephalin + H2O | - |
Bos taurus | Lys-Lys + (Met)enkephalin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 28000, SDS-PAGE | Mus musculus |
? | x * 28000, SDS-PAGE | Bos taurus |
General Information | Comment | Organism |
---|---|---|
malfunction | knockout of the cathepsin H gene results in 50% reduction of (Met)enkephalin in mouse brain. Cathepsin H deficient mice also show a substantial 80% decrease in galanin peptide neurotransmitter levels in brain | Mus musculus |
physiological function | cathepsin H plays a role in enkephalin and galanin peptide neurotransmitter production | Mus musculus |
physiological function | cathepsin H plays a role in enkephalin and galanin peptide neurotransmitter production | Bos taurus |