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Literature summary for 3.4.22.15 extracted from

  • Hsu, K.F.; Wu, C.L.; Huang, S.C.; Wu, C.M.; Hsiao, J.R.; Yo, Y.T.; Chen, Y.H.; Shiau, A.L.; Chou, C.Y.
    Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells (2009), Autophagy, 5, 451-460.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Phe-Tyr-(tert-butyl)-diazomethylketone irreversible cathepsin L inhibitor Homo sapiens
trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cervical cancer cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
cat L
-
Homo sapiens

General Information

General Information Comment Organism
physiological function cat L mediates resveratrol-induced apoptotic cell death in cervical cancer cells Homo sapiens