Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.15 extracted from

  • Diederich, S.; Thiel, L.; Maisner, A.
    Role of endocytosis and cathepsin-mediated activation in Nipah virus entry (2008), Virology, 375, 391-400.
    View publication on PubMed

Application

Application Comment Organism
medicine activation of the Nipah virus fusion protein depends on a low pH value and the activity of cathepsin L in host cells Chlorocebus aethiops

Inhibitors

Inhibitors Comment Organism Structure
CA-074Me in cells transfected with Nipah virus fusion protein, treatment with inhibitor CA-074ME almost completely prevents proteolytic processing of F0 into F1 and F2 Chlorocebus aethiops
E-64d in cells transfected with Nipah virus fusion protein, treatment with inhibitor E-64d almost completely prevents proteolytic processing of F0 into F1 and F2 Chlorocebus aethiops

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Chlorocebus aethiops
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Vero cell
-
Chlorocebus aethiops
-