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Literature summary for 3.4.22.15 extracted from

  • Liu, Y.; Li, X.; Peng, D.; Tan, Z.; Liu, H.; Qing, Y.; Xue, Y.; Shi, G.P.
    Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease (2009), Am. J. Cardiol., 103, 476-481.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine serum cathepsin L levels are significantly higher in patients with coronary heart disease than in those without coronary heart disease. Patients with unstable angina pectoris have higher serum cathepsin L levels than those with stable angina pectoris. Of patients with acute coronary syndrome, those with acute myocardial infarction have higher serum cathepsin L levels than those with unstable angina pectoris, and patients with previous myocardial infarction have the highest levels. Serum cathepsin L associates positively with number of coronary branch luminal narrowings, Gensini scores, high-sensitivity C-reactive protein, fasting glucose, and cigarette smokers, but inversely with high-density lipoprotein and apolipoprotein A1 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with coronary heart disease
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Source Tissue

Source Tissue Comment Organism Textmining
aorta increased level of cathepsin L in atherosclerotic lesions compared with healthy aortas Homo sapiens
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