Literature summary for 3.4.21.B25 extracted from

Lin, Y.E.; Wu, Q.N.; Lin, X.D.; Li, G.Q.; Zhang, Y.J.
Expression of paired basic amino acid-cleaving enzyme 4 (PACE4) correlated with prognosis in non-small cell lung cancer (NSCLC) patients (2015), J. Thorac. Dis., 7, 850-860 .

Search for more literature for 3.4.21.B25

Application

Application	Comment	Organism
diagnostics	expression of the enzyme correlates with prognosis in non-small cell lung cancer patients. Overall survival is significantly prolonged in PACE4 negative group when compared with PACE4 positive group (5-year survival rates, 23.1% vs. 54.5%, log-rank test), as is disease-free survival (5-year survival rates, 23.4% vs. 55.4%). Positive expression of PACE4 is an independent factor for non-small cell lung cancer patients and it might serve as a potential prognostic biomarker for patients with non-small cell lung cancer	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P29122	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
16-HBE14o cell	-	Homo sapiens	-
lung	enzyme expression in non-small cell lung cancer cells is significantly higher than in normal lung cell and tissues	Homo sapiens	-
non-small cell lung cancer cell line	enzyme expression in non-small cell lung cancer cells is significantly higher than in normal lung cell and tissues	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PACE4	-	Homo sapiens
paired basic amino acid-cleaving enzyme 4	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)